MolNFT v1 · #44588 · protein
A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor displacement
2MC6 · RNA polymerase inhibitor P7: “A bacteriophage transcription regulator inhibits bacterial transcription initiation by sigma-factor…”. Solution nmr. MolNFT v1 #44588 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2MC6
- Type
- protein
- Length
- 83 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- RNA polymerase inhibitor P7; DNA-directed RNA polymerase subunit beta'
- EC
- 2.7.7.6
- UniProt
- Q8LTJ5, Q8KTH8
Structure
solution nmr · 2 distinct chains · 30% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA polymerase inhibitor P7 | protein | 73 | 27% helix, 27% strand | Q8LTJ5 |
| B | DNA-directed RNA polymerase subunit beta' (EC 2.7.7.6) | protein | 10 | 50% helix, 0% strand | Q8KTH8 |
Interfaces
1 interface between chains.
- A–B · 531 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
- 2MC6 · A bacteriophage transcription regulator inhibits bacterial transcription initiation by… · the same entry in another collection · chain A against A, TM-score 1.00
- Q8KTH8 · AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit beta' (Q8KTH8) · a predicted model of the same protein · chain B against A, TM-score 0.45
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8LTJ5
- Every structure of UniProt Q8KTH8
- Elsewhere: RCSB PDB 2MC6 · PDBe 2MC6 · UniProt Q8LTJ5 · UniProt Q8KTH8
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