MolNFT v1 · #44506 · protein

RBPMS2-NTER

2M9K · RNA-binding protein with multiple splicing 2: “RBPMS2-NTER”. Solution nmr, 1 pocket (best druggability 0.36). MolNFT v1 #44506 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2M9K
Type: protein
Length: 186 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA-binding protein with multiple splicing 2
UniProt: Q6ZRY4
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 20% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	RNA-binding protein with multiple splicing 2	protein	93	20% helix, 28% strand	Q6ZRY4

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.36	0.78	16	empty

Interfaces

1 interface between chains.

A–B · 766 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

2M9K · RBPMS2-Nter · the same entry in another collection · chain A against A, TM-score 1.00
Q6ZRY4 · AlphaFold monomer V2.0 prediction for RNA-binding protein with multiple splicing 2… · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6ZRY4
Elsewhere: RCSB PDB 2M9K · PDBe 2M9K · UniProt Q6ZRY4

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