MolNFT v1 · #44362 · protein
Solution structure of the bacillus cereus metallo-beta-lactamase bcii
2M5C · Beta-lactamase 2: “Solution structure of the bacillus cereus metallo-beta-lactamase bcii”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.40). MolNFT v1 #44362 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2M5C
- Type
- protein
- Length
- 227 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-lactamase 2
- EC
- 3.5.2.6
- UniProt
- P04190
- Ligands
- ZN
- Pockets
- 1 · best druggability 0.40
Structure
solution nmr · 1 distinct chain · 22% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Beta-lactamase 2 (EC 3.5.2.6) | protein | 227 | 22% helix, 22% strand | P04190 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 119 | 0.40 | 0.75 | 27 | empty |
Compared structures
- 2M5C · Solution Structure of the Bacillus cereus Metallo-Beta-Lactamase BcII · the same entry in another collection · chain A against A, TM-score 1.00
- P04190 · AlphaFold monomer V2.0 prediction for metallo-beta-lactamase type 2 (P04190) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04190
- Elsewhere: RCSB PDB 2M5C · PDBe 2M5C · UniProt P04190
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