MolNFT v1 · #44353 · DNA
G-rich VEGF aptamer with lna modifications
2M53: “G-rich VEGF aptamer with lna modifications”. Solution nmr, 1 pocket (best druggability 0.35). MolNFT v1 #44353 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2M53
- Type
- DNA
- Length
- 25 nucleotides
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- G-rich VEGF aptamer
- Pockets
- 1 · best druggability 0.35
Structure
solution nmr · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | G-rich VEGF aptamer | dna | 25 | — | — |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 107 | 0.35 | 0.74 | 12 | empty |
Modifications
Observed in the structure: 3 modified (nucleotide modification).
Compared structures
- 2M53 · G-rich VEGF aptamer with LNA modifications · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2M53 · PDBe 2M53
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