MolNFT v1 · #44239 · DNA

Parallel human telomeric quadruplex containing 2'F-ana substitutions

2M1G · 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(GFL)P*GP*GP*T)-3': “Parallel human telomeric quadruplex containing 2'F-ana substitutions”. Solution nmr. MolNFT v1 #44239 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2M1G
Type: DNA
Length: 24 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'-D(*TP*AP*GP*GP*GP*TP*TP*AP*(GFL)P*GP*GP*T)-3'

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	5'-D(TPAPGPGPGPTPTPAP(GFL)PGPGPT)-3'	dna	12	—	—

Interfaces

1 interface between chains.

A–B · 367 Å² buried · 24 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 2 modified (nucleotide modification).

Compared structures

2M1G · Parallel human telomeric quadruplex containing 2'F-ANA substitutions · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2M1G · PDBe 2M1G

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