MolNFT v1 · #44212 · protein

The solution structure of human PHF1 in complex with H3K36ME3

2M0O · Phd finger protein 1: “The solution structure of human PHF1 in complex with H3K36ME3”. Solution nmr. MolNFT v1 #44212 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2M0O
Type: protein
Length: 90 residues
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phd finger protein 1; H3K36ME3 peptide
UniProt: O43189

Structure

solution nmr · 2 distinct chains · 0% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phd finger protein 1	protein	79	0% helix, 30% strand	O43189
B	H3K36ME3 peptide	protein	11	0% helix, 0% strand	—

Interfaces

1 interface between chains.

A–B · 421 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 modified (methylation).

Compared structures

2M0O · The solution structure of human PHF1 in complex with H3K36me3 · the same entry in another collection · chain A against A, TM-score 1.00
O43189 · AlphaFold monomer V2.0 prediction for phd finger protein 1 (O43189) · a predicted model of the same protein · chain A against A, TM-score 0.62

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O43189
Elsewhere: RCSB PDB 2M0O · PDBe 2M0O · UniProt O43189

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