MolNFT v1 · #44193 · protein
Solution structure of BCL-xl determined with selective isotope labelling of I,L,V sidechains
2M03 · BCL-2-like protein 1: “Solution structure of BCL-xl determined with selective isotope labelling of I,L,V sidechains”. Solution nmr, 4 pockets (best druggability 0.55). MolNFT v1 #44193 on GenesisL1: 3D structure, binding sites and…
- PDB
- 2M03
- Type
- protein
- Length
- 177 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- BCL-2-like protein 1
- UniProt
- Q07817
- Pockets
- 4 · best druggability 0.55
Structure
solution nmr · 1 distinct chain · 64% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | BCL-2-like protein 1 | protein | 177 | 64% helix, 0% strand | Q07817 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 263 | 0.55 | 0.77 | 32 | empty |
| 2 | 104 | 0.49 | 0.81 | 21 | empty |
| 3 | 101 | 0.47 | 0.80 | 20 | empty |
| 4 | 93 | 0.38 | 0.76 | 18 | empty |
Compared structures
- 2M03 · Solution structure of BCL-xL determined with selective isotope labelling of I,L,V… · the same entry in another collection · chain A against A, TM-score 1.00
- Q07817 · AlphaFold monomer V2.0 prediction for BCL-2-like protein 1 (Q07817) · a predicted model of the same protein · chain A against A, TM-score 0.71
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q07817
- Elsewhere: RCSB PDB 2M03 · PDBe 2M03 · UniProt Q07817
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