MolNFT v1 · #44076 · RNA

Solution structure of small molecule-influenza RNA complex

2LWK · RNA (32-mer): “Solution structure of small molecule-influenza RNA complex”. Solution nmr, 1 ligand (0EC), 1 pocket (best druggability 0.30). MolNFT v1 #44076 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LWK
Type: RNA
Length: 32 nucleotides
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA (32-mer)
Ligands: 0EC
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (32-mer)	rna	32	—	—

Ligands and binding sites

0EC · 6,7-dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.30	0.72	10	empty

Compared structures

2LWK · Solution structure of small molecule-influenza RNA complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2LWK · PDBe 2LWK

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