MolNFT v1 · #44011 · protein
NMR solution structure of apo-mptpa
2LUO · Low molecular weight protein-tyrosine-phosphatase a: “NMR solution structure of apo-mptpa”. Solution nmr, 2 pockets (best druggability 0.47). MolNFT v1 #44011 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2LUO
- Type
- protein
- Length
- 164 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Low molecular weight protein-tyrosine-phosphatase a
- EC
- 3.1.3.48
- UniProt
- P65716
- Pockets
- 2 · best druggability 0.47
Structure
solution nmr · 1 distinct chain · 44% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Low molecular weight protein-tyrosine-phosphatase a (EC 3.1.3.48) | protein | 164 | 44% helix, 15% strand | P65716 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.47 | 0.84 | 22 | empty |
| 2 | 61 | 0.28 | 0.74 | 16 | empty |
Compared structures
- 2LUO · NMR solution structure of apo-MptpA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P65716
- Elsewhere: RCSB PDB 2LUO · PDBe 2LUO · UniProt P65716
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