MolNFT v1 · #43986 · protein
SMURF1 WW2 domain in complex with a SMAD7 derived peptide
2LTX · E3 ubiquitin-protein ligase SMURF1: “SMURF1 WW2 domain in complex with a SMAD7 derived peptide”. Solution nmr. MolNFT v1 #43986 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2LTX
- Type
- protein
- Length
- 50 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E3 ubiquitin-protein ligase SMURF1; SMAD7 derived peptide
- UniProt
- Q9HCE7, O15105
Structure
solution nmr · 2 distinct chains · 0% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | E3 ubiquitin-protein ligase SMURF1 | protein | 35 | 0% helix, 43% strand | Q9HCE7 |
| B | SMAD7 derived peptide | protein | 15 | 0% helix, 0% strand | O15105 |
Interfaces
1 interface between chains.
- A–B · 617 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 2LTX · Smurf1 WW2 domain in complex with a Smad7 derived peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q9HCE7 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SMURF1 (Q9HCE7) · a predicted model of the same protein · chain A against A, TM-score 0.54
- O15105 · AlphaFold monomer V2.0 prediction for mothers against decapentaplegic homolog 7 (O15105) · a predicted model of the same protein · chain B against A, TM-score 0.34
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HCE7
- Every structure of UniProt O15105
- Elsewhere: RCSB PDB 2LTX · PDBe 2LTX · UniProt Q9HCE7 · UniProt O15105
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