MolNFT v1 · #43978 · protein

Solution structure of the SANT2 domain of the human nuclear receptor corepressor 2 (NCOR2), northeast structural genomics consortium (nesg) target id HR4636E

2LTP: “Solution structure of the SANT2 domain of the human nuclear receptor corepressor 2 (NCOR2), northeast…”. Solution nmr, 1 pocket (best druggability 0.40). MolNFT v1 #43978 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LTP
Type: protein
Length: 71 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuclear receptor corepressor 2
UniProt: Q9Y618
Pockets: 1 · best druggability 0.40

Structure

solution nmr · 1 distinct chain · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear receptor corepressor 2	protein	71	69% helix, 0% strand	Q9Y618

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	70	0.40	0.78	11	empty

Compared structures

2LTP · Solution structure of the SANT2 domain of the human nuclear receptor corepressor 2… · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y618 · AlphaFold monomer V2.0 prediction for nuclear receptor corepressor 2 (Q9Y618) · a predicted model of the same protein · chain A against A, TM-score 0.68

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y618
Elsewhere: RCSB PDB 2LTP · PDBe 2LTP · UniProt Q9Y618

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