MolNFT v1 · #43960 · protein

Zymogen-flg of the onconase

2LT5 · Protein P-30: “Zymogen-flg of the onconase”. Solution nmr, 2 pockets (best druggability 0.46). MolNFT v1 #43960 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LT5
Type: protein
Length: 120 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein P-30
EC: 3.1.27.-
UniProt: P22069
Pockets: 2 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 10% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein P-30 (EC 3.1.27.-)	protein	120	10% helix, 30% strand	P22069

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	129	0.46	0.78	19	empty
2	64	0.30	0.75	17	empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

2LT5 · Zymogen-FLG of the onconase · the same entry in another collection · chain A against A, TM-score 1.00
P22069 · AlphaFold monomer V2.0 prediction for protein P-30 (P22069) · a predicted model of the same protein · chain A against A, TM-score 0.49

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P22069
Elsewhere: RCSB PDB 2LT5 · PDBe 2LT5 · UniProt P22069

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