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MolNFT v1 · #43946 · protein

Solution structure of harmonin N terminal domain in complex with a EXON68 encoded peptide of CADHERIN23

2LSR: “Solution structure of harmonin N terminal domain in complex with a EXON68 encoded peptide of CADHERIN23”. Solution nmr. MolNFT v1 #43946 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2LSR
Type
protein
Length
96 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Harmonin; Peptide from cadherin-23
UniProt
Q9Y6N9, F6U049

Structure

solution nmr · 2 distinct chains · 78% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHarmoninprotein8078% helix, 0% strandQ9Y6N9
BPeptide from cadherin-23protein1681% helix, 0% strandF6U049

Interfaces

1 interface between chains.

  • A–B · 726 Ų buried · 4 hydrogen bonds · protein-protein

Compared structures

  • 2LSR · Solution structure of harmonin N terminal domain in complex with a exon68 encoded peptide… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9Y6N9 · AlphaFold monomer V2.0 prediction for harmonin (Q9Y6N9) · a predicted model of the same protein · chain A against A, TM-score 0.85

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