MolNFT v1 · #43816 · protein

Backbone structure of human membrane protein TMEM141

2LOR · Transmembrane protein 141: “Backbone structure of human membrane protein TMEM141”. Solution nmr, 1 pocket (best druggability 0.49). MolNFT v1 #43816 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LOR
Type: protein
Length: 108 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transmembrane protein 141
UniProt: Q96I45
Pockets: 1 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transmembrane protein 141	protein	108	72% helix, 0% strand	Q96I45

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	152	0.49	0.78	21	empty

Compared structures

2LOR · Backbone structure of human membrane protein TMEM141 · the same entry in another collection · chain A against A, TM-score 1.00
Q96I45 · AlphaFold monomer V2.0 prediction for transmembrane protein 141 (Q96I45) · a predicted model of the same protein · chain A against A, TM-score 0.49

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96I45
Elsewhere: RCSB PDB 2LOR · PDBe 2LOR · UniProt Q96I45

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