MolNFT v1 · #43811 · protein

Backbone structure of human membrane protein HIGD1A

2LOM · HIG1 domain family member 1A: “Backbone structure of human membrane protein HIGD1A”. Solution nmr, 1 pocket (best druggability 0.37). MolNFT v1 #43811 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LOM
Type: protein
Length: 93 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: HIG1 domain family member 1A
UniProt: Q9Y241
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 44% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	HIG1 domain family member 1A	protein	93	44% helix, 0% strand	Q9Y241

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.37	0.75	14	empty

Compared structures

2LOM · Backbone structure of human membrane protein HIGD1A · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y241 · AlphaFold monomer V2.0 prediction for HIG1 domain family member 1A, mitochondrial (Q9Y241) · a predicted model of the same protein · chain A against A, TM-score 0.37

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y241
Elsewhere: RCSB PDB 2LOM · PDBe 2LOM · UniProt Q9Y241

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