MolNFT v1 · #43777 · protein
Enterohaemorrhagic E. COLI (ehec) exploits a tryptophan switch to hijack host F-actin assembly
2LNH · Neural wiskott-aldrich syndrome protein: “Enterohaemorrhagic E. COLI (ehec) exploits a tryptophan switch to hijack host F-actin assembly”. Solution nmr. MolNFT v1 #43777 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2LNH
- Type
- protein
- Length
- 179 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neural wiskott-aldrich syndrome protein; Brain-specific angiogenesis inhibitor…
- UniProt
- O00401, Q9UHR4, P0DJ89
Structure
solution nmr · 3 distinct chains · 27% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neural wiskott-aldrich syndrome protein | protein | 65 | 48% helix, 6% strand | O00401 |
| B | Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 | protein | 67 | 4% helix, 39% strand | Q9UHR4 |
| C | Secreted effector protein ESPF(U) | protein | 47 | 30% helix, 0% strand | P0DJ89 |
Interfaces
2 interfaces between chains.
- B–C · 782 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 771 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 2LNH · Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UHR4 · AlphaFold monomer V2.0 prediction for brain-specific angiogenesis inhibitor 1-associated… · a predicted model of the same protein · chain B against A, TM-score 0.86
- O00401 · AlphaFold monomer V2.0 prediction for neural wiskott-aldrich syndrome protein (O00401) · a predicted model of the same protein · chain A against A, TM-score 0.76
- P0DJ89 · AlphaFold monomer V2.0 prediction for secreted effector protein ESPF(U) (P0DJ89) · a predicted model of the same protein · chain C against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O00401
- Every structure of UniProt Q9UHR4
- Every structure of UniProt P0DJ89
- Elsewhere: RCSB PDB 2LNH · PDBe 2LNH · UniProt O00401 · UniProt Q9UHR4 · UniProt P0DJ89
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