MolNFT v1 · #43714 · protein

Sixth gelsolin-like domain of villin in 5 mm CACL2

2LLF · Villin-1: “Sixth gelsolin-like domain of villin in 5 mm CACL2”. Solution nmr, 1 pocket (best druggability 0.43). MolNFT v1 #43714 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2LLF
Type: protein
Length: 107 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Villin-1
UniProt: P02640
Pockets: 1 · best druggability 0.43

Structure

solution nmr · 1 distinct chain · 25% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Villin-1	protein	107	25% helix, 23% strand	P02640

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.43	0.80	21	empty

Compared structures

2LLF · Sixth Gelsolin-like domain of villin in 5 mM CaCl2 · the same entry in another collection · chain A against A, TM-score 1.00
P02640 · AlphaFold monomer V2.0 prediction for villin-1 (P02640) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02640
Elsewhere: RCSB PDB 2LLF · PDBe 2LLF · UniProt P02640

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