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MolNFT v1 · #43711 · protein

NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor

2LLA · Mannose-6-PHOSPHATE/INSULIN-like growth factor II receptor: “NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor”. Solution nmr, 1 pocket (best druggability 0.50). MolNFT v1 #43711 on GenesisL1: 3D…

PDB
2LLA
Type
protein
Length
140 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Mannose-6-PHOSPHATE/INSULIN-like growth factor II receptor
UniProt
Q95LC7
Pockets
1 · best druggability 0.50

Structure

solution nmr · 1 distinct chain · 6% helix, 43% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMannose-6-PHOSPHATE/INSULIN-like growth factor II receptorprotein1406% helix, 43% strandQ95LC7

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11040.500.8121empty

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

  • 2LLA · NMR solution structure ensemble of domain 11 of the echidna M6P/IGF2R receptor · the same entry in another collection · chain A against A, TM-score 1.00

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