MolNFT v1 · #43642 · protein
Solution structure of ADF/COFILIN from trypanosoma brucei
2LJ8 · COFILIN/ACTIN depolymerizing factor, putative: “Solution structure of ADF/COFILIN from trypanosoma brucei”. Solution nmr, 1 pocket (best druggability 0.63). MolNFT v1 #43642 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2LJ8
- Type
- protein
- Length
- 136 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- COFILIN/ACTIN depolymerizing factor, putative
- UniProt
- Q580V7
- Pockets
- 1 · best druggability 0.63
Structure
solution nmr · 1 distinct chain · 35% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | COFILIN/ACTIN depolymerizing factor, putative | protein | 136 | 35% helix, 28% strand | Q580V7 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 179 | 0.63 | 0.83 | 24 | empty |
Compared structures
- 2LJ8 · Solution structure of ADF/Cofilin from trypanosoma brucei · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q580V7
- Elsewhere: RCSB PDB 2LJ8 · PDBe 2LJ8 · UniProt Q580V7
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