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MolNFT v1 · #43291 · DNA

A biocompatible backbone modification? - structure and dynamics of a triazole-linked DNA duplex

2L8I · DNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3'): “A biocompatible backbone modification? - structure and dynamics of a triazole-linked DNA duplex”. Solution nmr. MolNFT v1 #43291 on GenesisL1: 3D structure, binding sites and…

PDB
2L8I
Type
DNA
Length
25 nucleotides
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3'); DNA…

Structure

solution nmr · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA (5'-D(*GP*CP*TP*GP*CP*AP*AP*AP*CP*GP*TP*CP*G)-3')dna13——
BDNA (5'-D(*CP*GP*AP*CP*G*(2L8)P*TP*GP*CP*AP*GP*C)-3')dna12——

Interfaces

1 interface between chains.

  • A–B · 608 Ų buried · 81 hydrogen bonds · nucleic-nucleic

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Compared structures

  • 2L8I · A biocompatible backbone modification? - Structure and dynamics of a triazole-linked DNA… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

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