MolNFT v1 · #43275 · protein
Solution NMR structure of the serine-rich domain of HEF1 (enhancer of filamentation 1) from homo sapiens, northeast structural genomics consortium target HR5554A
2L81: “Solution NMR structure of the serine-rich domain of HEF1 (enhancer of filamentation 1) from homo sapiens…”. Solution nmr, 1 pocket (best druggability 0.36). MolNFT v1 #43275 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 2L81
- Type
- protein
- Length
- 176 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enhancer of filamentation 1
- UniProt
- Q14511
- Pockets
- 1 · best druggability 0.36
Structure
solution nmr · 1 distinct chain · 66% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Enhancer of filamentation 1 | protein | 176 | 66% helix, 0% strand | Q14511 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 66 | 0.36 | 0.78 | 18 | empty |
Compared structures
- 2L81 · Solution NMR Structure of the serine-rich domain of hEF1 (Enhancer of filamentation 1)… · the same entry in another collection · chain A against A, TM-score 1.00
- Q14511 · AlphaFold monomer V2.0 prediction for enhancer of filamentation 1 (Q14511) · a predicted model of the same protein · chain A against A, TM-score 0.88
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q14511
- Elsewhere: RCSB PDB 2L81 · PDBe 2L81 · UniProt Q14511
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