MolNFT v1 · #43270 · protein

Solution structure of the human RAF-1 kinase inhibitor protein

2L7W · Phosphatidylethanolamine-binding protein 1: “Solution structure of the human RAF-1 kinase inhibitor protein”. Solution nmr, 1 pocket (best druggability 0.37). MolNFT v1 #43270 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2L7W
Type: protein
Length: 187 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphatidylethanolamine-binding protein 1
UniProt: P30086
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 13% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphatidylethanolamine-binding protein 1	protein	187	13% helix, 27% strand	P30086

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	83	0.37	0.76	15	empty

Compared structures

2L7W · Solution structure of the human Raf-1 kinase inhibitor protein · the same entry in another collection · chain A against A, TM-score 1.00
P30086 · AlphaFold monomer V2.0 prediction for phosphatidylethanolamine- binding protein 1 (P30086) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P30086
Elsewhere: RCSB PDB 2L7W · PDBe 2L7W · UniProt P30086

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