MolNFT v1 · #43219 · protein
NMR structure of the monomeric mutant C-terminal domain of HIV-1 capsid in complex with stapled peptide inhibitor
2L6E · Capsid protein P24: “NMR structure of the monomeric mutant C-terminal domain of HIV-1 capsid in complex with stapled peptide…”. Solution nmr. MolNFT v1 #43219 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2L6E
- Type
- protein
- Length
- 108 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid protein P24; Nyad-13 stapled peptide inhibitor
- UniProt
- P35963
Structure
solution nmr · 2 distinct chains · 52% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid protein P24 | protein | 94 | 50% helix, 0% strand | P35963 |
| B | Nyad-13 stapled peptide inhibitor | protein | 14 | 64% helix, 0% strand | — |
Interfaces
1 interface between chains.
- A–B · 770 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (nonstandard).
Compared structures
- 2L6E · NMR Structure of the monomeric mutant C-terminal domain of HIV-1 Capsid in complex with… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35963
- Elsewhere: RCSB PDB 2L6E · PDBe 2L6E · UniProt P35963
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