MolNFT v1 · #43125 · protein
Solution structure of murine interleukin 3
2L3O: “Solution structure of murine interleukin 3”. Solution nmr, 2 pockets (best druggability 0.36). MolNFT v1 #43125 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2L3O
- Type
- protein
- Length
- 124 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Interleukin 3
- UniProt
- Q5SX77
- Pockets
- 2 · best druggability 0.36
Structure
solution nmr · 1 distinct chain · 43% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Interleukin 3 | protein | 124 | 43% helix, 0% strand | Q5SX77 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.36 | 0.79 | 18 | empty |
| 2 | 56 | 0.30 | 0.75 | 12 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 2L3O · Solution structure of murine interleukin 3 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SX77
- Elsewhere: RCSB PDB 2L3O · PDBe 2L3O · UniProt Q5SX77
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