MolNFT v1 · #43117 · protein

Solution NMR structure of a putative uracil DNA glycosylase from methanosarcina acetivorans, northeast structural genomics consortium target MVR76

2L3F · Uncharacterized protein: “Solution NMR structure of a putative uracil DNA glycosylase from methanosarcina acetivorans, northeast…”. Solution nmr, 1 pocket (best druggability 0.61). MolNFT v1 #43117 on GenesisL1: 3D structure…

PDB: 2L3F
Type: protein
Length: 161 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: Q8TTH3
Pockets: 1 · best druggability 0.61

Structure

solution nmr · 1 distinct chain · 36% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	161	36% helix, 18% strand	Q8TTH3

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	155	0.61	0.84	27	empty

Compared structures

2L3F · Solution NMR Structure of a putative Uracil DNA glycosylase from Methanosarcina… · the same entry in another collection · chain A against A, TM-score 1.00
Q8TTH3 · AlphaFold monomer V2.0 prediction for hypoxanthine DNA glycosylase (Q8TTH3) · a predicted model of the same protein · chain A against A, TM-score 0.90

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TTH3
Elsewhere: RCSB PDB 2L3F · PDBe 2L3F · UniProt Q8TTH3

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