MolNFT v1 · #42838 · protein + DNA
Tetrapeptide kwkk conjugated to oligonucleotide duplex by a trimethylene tether
2KV6 · 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3': “Tetrapeptide kwkk conjugated to oligonucleotide duplex by a trimethylene tether”. Solution nmr. MolNFT v1 #42838 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KV6
- Type
- protein + DNA
- Length
- 28 residues
- Chains
- 3
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3'; 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3'…
Structure
solution nmr · 3 distinct chains · 0% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3' | dna | 12 | — | — |
| B | 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3' | dna | 12 | — | — |
| C | Kwkk tetrapeptide | protein | 4 | 0% helix, 0% strand | — |
Interfaces
3 interfaces between chains.
- A–B · 557 Ų buried · 58 hydrogen bonds · nucleic-nucleic
- A–C · 139 Ų buried · 1 hydrogen bond · protein-nucleic
- B–C · 129 Ų buried · 1 hydrogen bond · protein-nucleic
Modifications
Observed in the structure: 1 modified (nucleotide modification).
Compared structures
- 2KV6 · Tetrapeptide KWKK conjugated to oligonucleotide duplex by a trimethylene tether · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2KV6 · PDBe 2KV6
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