MolNFT v1 · #42718 · protein

Solution structure of E4B/UFD2A U-box domain

2KRE · Ubiquitin conjugation factor E4 B: “Solution structure of E4B/UFD2A U-box domain”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1 #42718 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KRE
Type: protein
Length: 100 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin conjugation factor E4 B
UniProt: O95155
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 19% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin conjugation factor E4 B	protein	100	19% helix, 14% strand	O95155

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	118	0.41	0.76	25	empty

Compared structures

2KRE · Solution structure of E4B/UFD2A U-Box domain · the same entry in another collection · chain A against A, TM-score 1.00
O95155 · AlphaFold monomer V2.0 prediction for ubiquitin conjugation factor E4 B (O95155) · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95155
Elsewhere: RCSB PDB 2KRE · PDBe 2KRE · UniProt O95155

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