MolNFT v1 · #42611 · protein
Solution NMR structure of the act domain from GTP pyrophosphokinase of chlorobium tepidum. northeast structural genomics consortium target CTR148A
2KO1: “Solution NMR structure of the act domain from GTP pyrophosphokinase of chlorobium tepidum. northeast…”. Solution nmr, 1 pocket (best druggability 0.46). MolNFT v1 #42611 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KO1
- Type
- protein
- Length
- 176 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- GTP pyrophosphokinase
- EC
- 2.7.6.5
- UniProt
- Q8KC80
- Pockets
- 1 · best druggability 0.46
Structure
solution nmr · 1 distinct chain · 23% helix, 40% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | GTP pyrophosphokinase (EC 2.7.6.5) | protein | 88 | 23% helix, 40% strand | Q8KC80 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 158 | 0.46 | 0.76 | 26 | empty |
Interfaces
1 interface between chains.
- A–B · 844 Ų buried · 32 hydrogen bonds · protein-protein
Compared structures
- 2KO1 · Solution NMR structure of the ACT domain from GTP pyrophosphokinase of Chlorobium… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8KC80
- Elsewhere: RCSB PDB 2KO1 · PDBe 2KO1 · UniProt Q8KC80
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