MolNFT v1 · #42541 · protein

Solution structure of human ubiquitin conjugating enzyme UBE2G2

2KLY · Ubiquitin-conjugating enzyme E2 G2: “Solution structure of human ubiquitin conjugating enzyme UBE2G2”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT v1 #42541 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KLY
Type: protein
Length: 165 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin-conjugating enzyme E2 G2
EC: 6.3.2.19
UniProt: P60604
Pockets: 1 · best druggability 0.31

Structure

solution nmr · 1 distinct chain · 32% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin-conjugating enzyme E2 G2 (EC 6.3.2.19)	protein	165	32% helix, 16% strand	P60604

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	78	0.31	0.73	17	empty

Compared structures

2KLY · Solution structure of human ubiquitin conjugating enzyme Ube2g2 · the same entry in another collection · chain A against A, TM-score 1.00
P60604 · AlphaFold monomer V2.0 prediction for ubiquitin-conjugating enzyme E2 G2 (P60604) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P60604
Elsewhere: RCSB PDB 2KLY · PDBe 2KLY · UniProt P60604

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