MolNFT v1 · #42536 · protein

Second CA2+ binding domain of NCX1.3

2KLT · SODIUM/CALCIUM exchanger 1: “Second CA2+ binding domain of NCX1.3”. Solution nmr, 1 pocket (best druggability 0.48). MolNFT v1 #42536 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KLT
Type: protein
Length: 156 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: SODIUM/CALCIUM exchanger 1
Pockets: 1 · best druggability 0.48

Structure

solution nmr · 1 distinct chain · 5% helix, 38% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	SODIUM/CALCIUM exchanger 1	protein	156	5% helix, 38% strand	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	190	0.48	0.76	29	empty

Compared structures

2KLT · Second Ca2+ binding domain of NCX1.3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2KLT · PDBe 2KLT

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