MolNFT v1 · #42526 · protein

Structural basis for the photoconversion of a phytochrome to the activated far-red light-absorbing form

2KLI · Sensor protein: “Structural basis for the photoconversion of a phytochrome to the activated far-red light-absorbing form”. Solution nmr, 1 ligand (CYC), 4 pockets (best druggability 0.77). MolNFT v1 #42526 on GenesisL1: 3D…

PDB: 2KLI
Type: protein
Length: 172 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sensor protein
EC: 2.7.13.3
UniProt: Q2JIZ5
Ligands: CYC
Pockets: 4 · best druggability 0.77

Structure

solution nmr · 1 distinct chain · 35% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sensor protein (EC 2.7.13.3)	protein	172	35% helix, 20% strand	Q2JIZ5

Ligands and binding sites

CYC · Phycocyanobilin · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	455	0.77	0.85	49	CYC
2	58	0.42	0.81	17	empty
3	72	0.39	0.78	14	empty
4	96	0.37	0.75	28	empty

Modifications

Observed in the structure: 1 cofactor (phycocyanobilin attachment).

Compared structures

2KLI · Structural Basis for the Photoconversion of A Phytochrome to the Activated FAR-RED… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2JIZ5
Elsewhere: RCSB PDB 2KLI · PDBe 2KLI · UniProt Q2JIZ5

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