MolNFT v1 · #42486 · protein

NMR structure of the P62 PB1 domain

2KKC · Sequestosome-1: “NMR structure of the P62 PB1 domain”. Solution nmr, 1 pocket (best druggability 0.49). MolNFT v1 #42486 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KKC
Type: protein
Length: 100 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sequestosome-1
UniProt: O08623
Pockets: 1 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 22% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sequestosome-1	protein	100	22% helix, 37% strand	O08623

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.49	0.82	21	empty

Compared structures

2KKC · NMR structure of the p62 PB1 domain · the same entry in another collection · chain A against A, TM-score 1.00
O08623 · AlphaFold monomer V2.0 prediction for sequestosome-1 (O08623) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O08623
Elsewhere: RCSB PDB 2KKC · PDBe 2KKC · UniProt O08623

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