MolNFT v1 · #42440 · protein

Aida-1 SAM domain tandem

2KIV · Ankyrin repeat and sterile alpha motif domain-containing…: “Aida-1 SAM domain tandem”. Solution nmr, 2 pockets (best druggability 0.49). MolNFT v1 #42440 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2KIV
Type: protein
Length: 135 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ankyrin repeat and sterile alpha motif domain-containing protein 1B
UniProt: Q7Z6G8
Pockets: 2 · best druggability 0.49

Structure

solution nmr · 1 distinct chain · 53% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ankyrin repeat and sterile alpha motif domain-containing protein 1B	protein	135	53% helix, 1% strand	Q7Z6G8

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	96	0.49	0.81	22	empty
2	76	0.34	0.75	14	empty

Compared structures

2KIV · AIDA-1 SAM domain tandem · the same entry in another collection · chain A against A, TM-score 1.00
Q7Z6G8 · AlphaFold monomer V2.0 prediction for ankyrin repeat and sterile alpha motif… · a predicted model of the same protein · chain A against A, TM-score 0.84

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7Z6G8
Elsewhere: RCSB PDB 2KIV · PDBe 2KIV · UniProt Q7Z6G8

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