MolNFT v1 · #42439 · protein

Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: insight into its domain swapping

2KIU · Forkhead box protein P1: “Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: insight into its domain swapping”. Solution nmr, 1 pocket (best druggability 0.41). MolNFT v1 #42439 on GenesisL1: 3D structure…

PDB: 2KIU
Type: protein
Length: 87 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Forkhead box protein P1
UniProt: Q9H334
Pockets: 1 · best druggability 0.41

Structure

solution nmr · 1 distinct chain · 51% helix, 11% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Forkhead box protein P1	protein	87	51% helix, 11% strand	Q9H334

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	79	0.41	0.78	12	empty

Compared structures

2KIU · Solution structure and backbone dynamics of the DNA-binding domain of FOXP1: Insight into… · the same entry in another collection · chain A against A, TM-score 1.00
Q9H334 · AlphaFold monomer V2.0 prediction for forkhead box protein P1 (Q9H334) · a predicted model of the same protein · chain A against A, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H334
Elsewhere: RCSB PDB 2KIU · PDBe 2KIU · UniProt Q9H334

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