MolNFT v1 · #42426 · protein
A pH domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolism
2KIG · Inositol polyphosphate 5-phosphatase II isoform: “A pH domain within ocrl bridges clathrin mediated membrane trafficking to phosphoinositide metabolism”. Solution nmr, 3 pockets (best druggability 0.53). MolNFT v1 #42426 on…
- PDB
- 2KIG
- Type
- protein
- Length
- 161 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Inositol polyphosphate 5-phosphatase II isoform
- UniProt
- Q91ZF8
- Pockets
- 3 · best druggability 0.53
Structure
solution nmr · 1 distinct chain · 15% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Inositol polyphosphate 5-phosphatase II isoform | protein | 161 | 15% helix, 33% strand | Q91ZF8 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 56 | 0.53 | 0.87 | 16 | empty |
| 2 | 92 | 0.49 | 0.81 | 20 | empty |
| 3 | 100 | 0.47 | 0.80 | 17 | empty |
Compared structures
- 2KIG · A PH domain within OCRL bridges clathrin mediated membrane trafficking to… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q91ZF8
- Elsewhere: RCSB PDB 2KIG · PDBe 2KIG · UniProt Q91ZF8
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