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MolNFT v1 · #42392 · protein

Structural requirements for the uba domain of the mRNA export factor MEX67 to bind its specific targets, the transcription elongation tho complex component HPR1 and nucleoporin fxfg repeats

2KHH: “Structural requirements for the uba domain of the mRNA export factor MEX67 to bind its specific targets, the…”. Solution nmr. MolNFT v1 #42392 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2KHH
Type
protein
Length
66 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
MRNA export factor MEX67; Fxfg
UniProt
Q99257

Structure

solution nmr · 2 distinct chains · 50% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMRNA export factor MEX67protein5758% helix, 0% strandQ99257
BFxfgprotein90% helix, 0% strand—

Interfaces

1 interface between chains.

  • A–B · 459 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

  • 2KHH · Structural requirements for the UBA domain of the mRNA export factor Mex67 to bind its… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q99257 · AlphaFold monomer V2.0 prediction for mRNA export factor MEX67 (Q99257) · a predicted model of the same protein · chain A against A, TM-score 0.83

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