MolNFT v1 · #42336 · protein
NMR solution structure of the first phd finger domain of human autoimmune regulator (aire) in complex with histone H3(1-20CYS) peptide
2KFT: “NMR solution structure of the first phd finger domain of human autoimmune regulator (aire) in complex with…”. Solution nmr, 1 ligand (ZN). MolNFT v1 #42336 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KFT
- Type
- protein
- Length
- 77 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Autoimmune regulator; Histone H3
- UniProt
- O43918
- Ligands
- ZN
Structure
solution nmr · 2 distinct chains · 6% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Autoimmune regulator | protein | 56 | 9% helix, 14% strand | O43918 |
| B | Histone H3 | protein | 21 | 0% helix, 19% strand | — |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 655 Ų buried · 19 hydrogen bonds · protein-protein
Compared structures
- 2KFT · NMR Solution structure of the first PHD finger domain of human Autoimmune Regulator… · the same entry in another collection · chain A against A, TM-score 1.00
- O43918 · AlphaFold monomer V2.0 prediction for autoimmune regulator (O43918) · a predicted model of the same protein · chain A against A, TM-score 0.79
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O43918
- Elsewhere: RCSB PDB 2KFT · PDBe 2KFT · UniProt O43918
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