MolNFT v1 · #4230 · DNA

NMR solution structure of the DNA duplex containing DNA/RNA hybrid region, D(GG)R(AGAU)D(GAC)/D(GTCATCTCC)

1DHH · DNA/RNA (5'-D(*GP*G)-R(P*AP*GP*AP*U)-D(P*GP*AP*C)-3'): “NMR solution structure of the DNA duplex containing DNA/RNA hybrid region, D(GG)R(AGAU)D(GAC)/D(GTCATCTCC)”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #4230 on…

PDB: 1DHH
Type: DNA
Length: 18 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA/RNA (5'-D(*GP*G)-R(P*AP*GP*AP*U)-D(P*GP*AP*C)-3'); DNA…
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA/RNA (5'-D(GPG)-R(PAPGPAPU)-D(PGPAP*C)-3')	dna	9	—	—
B	DNA (5'-D(GPTPCPAPTPCPTPCP*C)-3')	dna	9	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.32	0.73	11	empty

Interfaces

1 interface between chains.

A–B · 400 Å² buried · 48 hydrogen bonds · nucleic-nucleic

Compared structures

1DHH · NMR solution structure of the DNA duplex containing DNA/RNA hybrid region… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 1DHH · PDBe 1DHH

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