MolNFT v1 · #42178 · protein
NMR structure of the MDVL1 PDZ domain in complex with its inhibitor
2KAW · Segment polarity protein dishevelled homolog dvl-1: “NMR structure of the MDVL1 PDZ domain in complex with its inhibitor”. Solution nmr, 1 ligand (SUZ). MolNFT v1 #42178 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 2KAW
- Type
- protein
- Length
- 90 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Segment polarity protein dishevelled homolog dvl-1
- UniProt
- P51141
- Ligands
- SUZ
Structure
solution nmr · 1 distinct chain · 13% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Segment polarity protein dishevelled homolog dvl-1 | protein | 90 | 13% helix, 33% strand | P51141 |
Ligands and binding sites
- SUZ · [(1Z)-5-fluoro-2-methyl-1-{4-[methylsulfinyl]benzylidene}-1H-inden-3-yl]acetic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 2KAW · NMR structure of the mDvl1 PDZ domain in complex with its inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
- P51141 · AlphaFold monomer V2.0 prediction for segment polarity protein dishevelled homolog dvl-1… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P51141
- Elsewhere: RCSB PDB 2KAW · PDBe 2KAW · UniProt P51141
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