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MolNFT v1 · #42110 · protein

Characterisation of the structural features and interactions of sclerostin: molecular insight into a key regulator of wnt-mediated bone formation

2K8P: “Characterisation of the structural features and interactions of sclerostin: molecular insight into a key…”. Solution nmr. MolNFT v1 #42110 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
2K8P
Type
protein
Length
189 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Sclerostin
UniProt
Q9BQB4

Structure

solution nmr · 1 distinct chain · 0% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASclerostinprotein1890% helix, 19% strandQ9BQB4

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

  • 2K8P · Characterisation of the structural features and interactions of sclerostin: molecular… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9BQB4 · AlphaFold monomer V2.0 prediction for sclerostin (Q9BQB4) · a predicted model of the same protein · chain A against A, TM-score 0.45

Analyse

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