MolNFT v1 · #42078 · protein

Human acylphosphatase (acph) common type

2K7K · Acylphosphatase-1: “Human acylphosphatase (acph) common type”. Solution nmr, 1 pocket (best druggability 0.79). MolNFT v1 #42078 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2K7K
Type: protein
Length: 99 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Acylphosphatase-1
EC: 3.6.1.7
UniProt: P07311
Pockets: 1 · best druggability 0.79

Structure

solution nmr · 1 distinct chain · 22% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Acylphosphatase-1 (EC 3.6.1.7)	protein	99	22% helix, 27% strand	P07311

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	187	0.79	0.94	39	empty

Compared structures

2K7K · Human Acylphosphatase (AcPh) common type · the same entry in another collection · chain A against A, TM-score 1.00
P07311 · AlphaFold monomer V2.0 prediction for acylphosphatase-1 (P07311) · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P07311
Elsewhere: RCSB PDB 2K7K · PDBe 2K7K · UniProt P07311

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