MolNFT v1 · #42066 · protein

Solution structure of the isdc neat domain bound to zinc protoporphyrin

2K78 · Iron-regulated surface determinant protein C: “Solution structure of the isdc neat domain bound to zinc protoporphyrin”. Solution nmr, 1 ligand (ZNH), 1 pocket (best druggability 0.57). MolNFT v1 #42066 on GenesisL1: 3D structure…

PDB: 2K78
Type: protein
Length: 126 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Iron-regulated surface determinant protein C
UniProt: Q7A151
Ligands: ZNH
Pockets: 1 · best druggability 0.57

Structure

solution nmr · 1 distinct chain · 2% helix, 55% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Iron-regulated surface determinant protein C	protein	126	2% helix, 55% strand	Q7A151

Ligands and binding sites

ZNH · Protoporphyrin IX containing Zn · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	133	0.57	0.82	22	ZNH

Compared structures

2K78 · Solution Structure of the IsdC NEAT domain bound to Zinc Protoporphyrin · the same entry in another collection · chain A against A, TM-score 1.00
Q7A151 · AlphaFold monomer V2.0 prediction for iron-regulated surface determinant protein C… · a predicted model of the same protein · chain A against A, TM-score 0.86

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7A151
Elsewhere: RCSB PDB 2K78 · PDBe 2K78 · UniProt Q7A151

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