MolNFT v1 · #42055 · protein

Autoregulation of a group 1 bacterial sigma factor involves the formation of a region 1.1- induced compacted structure

2K6X · RNA polymerase sigma factor rpod: “Autoregulation of a group 1 bacterial sigma factor involves the formation of a region 1.1- induced compacted…”. Solution nmr, 1 pocket (best druggability 0.55). MolNFT v1 #42055 on GenesisL1: 3D…

PDB: 2K6X
Type: protein
Length: 72 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA polymerase sigma factor rpod
UniProt: P77994
Pockets: 1 · best druggability 0.55

Structure

solution nmr · 1 distinct chain · 51% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA polymerase sigma factor rpod	protein	72	51% helix, 3% strand	P77994

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	101	0.55	0.83	18	empty

Compared structures

2K6X · Autoregulation of a Group 1 Bacterial Sigma Factor Involves the Formation of a Region… · the same entry in another collection · chain A against A, TM-score 1.00
P77994 · AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (P77994) · a predicted model of the same protein · chain A against A, TM-score 0.47

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P77994
Elsewhere: RCSB PDB 2K6X · PDBe 2K6X · UniProt P77994

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.