MolNFT v1 · #42027 · protein
Chemical shift structure of colicin E9 DNase domain with its cognate immunity protein IM9
2K5X · Colicin-E9 immunity protein: “Chemical shift structure of colicin E9 DNase domain with its cognate immunity protein IM9”. Solution nmr, 2 pockets (best druggability 0.39). MolNFT v1 #42027 on GenesisL1: 3D structure, binding sites…
- PDB
- 2K5X
- Type
- protein
- Length
- 220 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Colicin-E9 immunity protein; Colicin-E9
- EC
- 3.1.-.-
- UniProt
- P13479, P09883
- Pockets
- 2 · best druggability 0.39
Structure
solution nmr · 2 distinct chains · 43% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Colicin-E9 immunity protein | protein | 86 | 58% helix, 0% strand | P13479 |
| B | Colicin-E9 (EC 3.1.-.-) | protein | 134 | 33% helix, 16% strand | P09883 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 128 | 0.39 | 0.74 | 25 | empty |
| 2 | 63 | 0.33 | 0.77 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 861 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 2K5X · Chemical shift structure of COLICIN E9 DNASE domain with its cognate immunity protein IM9 · the same entry in another collection · chain B against B, TM-score 1.00
- P09883 · AlphaFold monomer V2.0 prediction for colicin-E9 (P09883) · a predicted model of the same protein · chain B against A, TM-score 0.93
- P13479 · AlphaFold monomer V2.0 prediction for colicin-E9 immunity protein (P13479) · a predicted model of the same protein · chain A against A, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13479
- Every structure of UniProt P09883
- Elsewhere: RCSB PDB 2K5X · PDBe 2K5X · UniProt P13479 · UniProt P09883
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.