MolNFT v1 · #41961 · protein
Solution structure of EAF3 chromo barrel domain bound to histone H3 with a dimethyllysine analog H3K36ME2
2K3Y · Chromatin modification-related protein EAF3: “Solution structure of EAF3 chromo barrel domain bound to histone H3 with a dimethyllysine analog H3K36ME2”. Solution nmr, 1 pocket (best druggability 0.39). MolNFT v1 #41961 on…
- PDB
- 2K3Y
- Type
- protein
- Length
- 134 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chromatin modification-related protein EAF3
- UniProt
- Q12432
- Pockets
- 1 · best druggability 0.39
Structure
solution nmr · 1 distinct chain · 18% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Chromatin modification-related protein EAF3 | protein | 134 | 18% helix, 24% strand | Q12432 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 115 | 0.39 | 0.75 | 21 | empty |
Modifications
Observed in the structure: 1 modified (nonstandard).
Compared structures
- 2K3Y · Solution structure of EAF3 chromo barrel domain bound to histone h3 with a dimethyllysine… · the same entry in another collection · chain A against A, TM-score 1.00
- Q12432 · AlphaFold monomer V2.0 prediction for chromatin modification-related protein EAF3 (Q12432) · a predicted model of the same protein · chain A against A, TM-score 0.68
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12432
- Elsewhere: RCSB PDB 2K3Y · PDBe 2K3Y · UniProt Q12432
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