MolNFT v1 · #41849 · protein

Zinc-finger 2 of NUP153

2K0C · Nuclear pore complex protein NUP153: “Zinc-finger 2 of NUP153”. Solution nmr, 1 ligand (ZN), 1 pocket (best druggability 0.30). MolNFT v1 #41849 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2K0C
Type: protein
Length: 35 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuclear pore complex protein NUP153
UniProt: P49791
Ligands: ZN
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 0% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear pore complex protein NUP153	protein	35	0% helix, 17% strand	P49791

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.30	0.74	18	empty

Compared structures

2K0C · Zinc-finger 2 of Nup153 · the same entry in another collection · chain A against A, TM-score 1.00
P49791 · AlphaFold monomer V2.0 prediction for nuclear pore complex protein NUP153 (P49791) · a predicted model of the same protein · chain A against A, TM-score 0.51

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49791
Elsewhere: RCSB PDB 2K0C · PDBe 2K0C · UniProt P49791

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