MolNFT v1 · #41769 · RNA

NMR structure of RNA duplex containing single adenosine bulge

2JXS · 5'-R(*GP*CP*AP*GP*AP*AP*GP*AP*GP*CP*G)-3': “NMR structure of RNA duplex containing single adenosine bulge”. Solution nmr, 1 pocket (best druggability 0.31). MolNFT v1 #41769 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2JXS
Type: RNA
Length: 21 nucleotides
Chains: 2
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 5'-R(*GP*CP*AP*GP*AP*AP*GP*AP*GP*CP*G)-3'; 5'-R(*CP*GP*CP*UP*CP*UP*CP*UP*GP*C)-3'
Pockets: 1 · best druggability 0.31

Structure

solution nmr · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	5'-R(GPCPAPGPAPAPGPAPGPCP*G)-3'	rna	11	—	—
B	5'-R(CPGPCPUPCPUPCPUPGPC)-3'	rna	10	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.31	0.72	13	empty

Interfaces

1 interface between chains.

A–B · 501 Å² buried · 63 hydrogen bonds · nucleic-nucleic

Compared structures

2JXS · NMR structure of RNA duplex containing single adenosine bulge · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2JXS · PDBe 2JXS

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