MolNFT v1 · #41747 · protein

NMR solution structure of the N-terminal domain of dek

2JX3 · Protein dek: “NMR solution structure of the N-terminal domain of dek”. Solution nmr, 1 pocket (best druggability 0.44). MolNFT v1 #41747 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2JX3
Type: protein
Length: 110 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Protein dek
UniProt: P35659
Pockets: 1 · best druggability 0.44

Structure

solution nmr · 1 distinct chain · 56% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Protein dek	protein	110	56% helix, 0% strand	P35659

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	99	0.44	0.78	15	empty

Compared structures

2JX3 · NMR solution structure of the N-terminal domain of DEK · the same entry in another collection · chain A against A, TM-score 1.00
P35659 · AlphaFold monomer V2.0 prediction for protein dek (P35659) · a predicted model of the same protein · chain A against A, TM-score 0.67

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35659
Elsewhere: RCSB PDB 2JX3 · PDBe 2JX3 · UniProt P35659

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