MolNFT v1 · #41743 · protein

Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins

2JWZ: “Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins”. Solution nmr, 1 pocket (best druggability 0.69). MolNFT v1 #41743 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 2JWZ
Type: protein
Length: 76 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ubiquitin
UniProt: P61864
Pockets: 1 · best druggability 0.69

Structure

solution nmr · 1 distinct chain · 20% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ubiquitin	protein	76	20% helix, 29% strand	P61864

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.69	0.95	21	empty

Compared structures

2JWZ · Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61864
Elsewhere: RCSB PDB 2JWZ · PDBe 2JWZ · UniProt P61864

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.