MolNFT v1 · #41513 · protein

NAB2 N-terminal domain

2JPS · Nuclear polyadenylated RNA-binding protein NAB2: “NAB2 N-terminal domain”. Solution nmr, 1 pocket (best druggability 0.32). MolNFT v1 #41513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 2JPS
Type: protein
Length: 105 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Nuclear polyadenylated RNA-binding protein NAB2
UniProt: P32505
Pockets: 1 · best druggability 0.32

Structure

solution nmr · 1 distinct chain · 71% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Nuclear polyadenylated RNA-binding protein NAB2	protein	105	71% helix, 0% strand	P32505

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	58	0.32	0.76	13	empty

Compared structures

2JPS · NAB2 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
P32505 · AlphaFold monomer V2.0 prediction for nuclear polyadenylated RNA- binding protein NAB2… · a predicted model of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32505
Elsewhere: RCSB PDB 2JPS · PDBe 2JPS · UniProt P32505

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